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Alexion Pharmaceuticals Alexion Product to Patient Project Manager (Possible Virtual/Remote) in Boston, Massachusetts


The Alexion Product to Patient Project Manager (AP2P Project Manager) provides foundational project management and administrative support to Alexion’s innovative approach to drug development—the Product to Patient model. Reporting into the AP2P Lead, this role supports the implementation and maintenance of Alexion’s Product to Patient operating model (AP2P), which serves as the operational umbrella to all initiatives advancing drug and device development across Alexion.

A key partner to the AP2P Lead, the AP2P working team, and Alexion’s Global Program Teams and Global Medicine Teams, the AP2P Project Manager connects relevant initiatives across Alexion to the AP2P model via project management essentials. This role will help functions to onboard to the new way of working and support them in developing specific strategies, guidance, training, and materials for integrating into the model. The AP2P Project Manager will lead by influence and work with a cross-functional team to develop operating model guidance and templates. This role will own the AP2P SharePoint, other relevant tools that support meeting management, elements of the AP2P playbook as well as update and implement AP2P planning and training materials for all levels of the organization.

The successful delivery of processes, guidance, and training for the AP2P model ties to the overall longevity of Alexion’s pipeline and lifecycle portfolio. Given the enterprise nature of the AP2P model, it is crucial that the AP2P Project Manager drives effective communication to and with key stakeholders across Alexion, consolidates data, and provides support to teams and functions as required.

Principal Responsibilities

  • Support the integration of initiatives under the AP2P umbrella by maintaining and developing tools, templates, metrics and analytics, and by providing administrative support for training to teams onboarding into the AP2P model

  • Establish deep knowledge of internal processes and requirements to deliver products to patients; function as a resource for information about governance meetings, providing operational support to functions and teams to integrate into cross-functional processes and to successfully execute on the Alexion portfolio

  • Drive continuous monitoring of AP2P implementation progress, goals, metrics, decisions and major milestones via respective project management tools; ensure action items are completed and decisions are implemented; maintain the decision and action log and elevate issues as necessary to the AP2P Lead and the AP2P working team, respectively and other appropriate functional leaders as needed

  • Support Global Medicine Team Leads, Global Program Team Leads, Global Program Managers and their respective asset/indication teams in implementing AP2P, navigating governance, driving stage gate reviews, and reporting

  • Support training of Global Medicine Teams, Global Program Teams, and relevant cross-functional sub-teams on the AP2P model team structure, governance, process, and decision-making approach

  • Support change management activities and materials as updates, improvements, and new initiatives are integrated into the AP2P model; drive documentation and ensure consistent material availability to all stakeholders, facilitate cross-functional alignment meetings and own the version control of AP2P materials

  • Maintain AP2P reference documents and templates; drive interlinking of respective materials for each initiative within the AP2P model to ensure data quality

  • Manage and oversee implementation of interactive tools (SharePoint, Team sites, etc.) to share AP2P guidance and foster team collaboration; facilitate alignment meetings across functions to ensure buy-in for implementation

  • Manage upfront planning and adherence to Alexion’s Stage Gate Review process by maintaining appropriate guidance, training, and documentation for the Global Program Teams on the AP2P SharePoint

  • Manage Governance meeting logistics, meeting preparation, attendance, and decision calendar

  • Prepare AP2P portfolio reports, track relevant KPIs, and proactively identify issues and work on mitigation plans

  • Drive win-win outcomes within the Strategic Planning and Portfolio Management (SPPM) team as well as across Project Manager functions by establishing and communicating expectations, motivating individuals, and providing honest and specific feedback

  • Work closely with the SPPM team, especially with the R&D Portfolio Management Operations team to identify and contribute to departmental process improvements and initiatives

Required Experience

  • Bachelor’s degree in life sciences or related field

  • Minimum of 3 years of experience in within one or more functional role(s) in pharmaceutical R&D drug development, biotechnology drug development, or related industry; R&D or enterprise operations experience preferred

  • Minimum of 3 years of experience managing and leading projects / programs in combination with 3-5 years within the biopharmaceutical or healthcare industry; R&D, Commercial or enterprise operations experience preferred

  • Track record in executing effective project management in cross-functional initiatives or program development teams

  • Knowledge of project management discipline and its application required to deliver time, cost, quality, and risk management to teams

  • Experience with strategic level reporting and systems needs of an R&D organization and building the appropriate practical solutions

  • Highly skilled in PM systems administration, design and maintenance, including analytical skills, decision-making capabilities, and excellent knowledge of software tools / solution principles (Microsoft Excel and PowerPoint, Smartsheet, SharePoint, One Pager Pro, etc.)

  • Demonstrated results in creating and managing complex project plans, including experience with global teams, budget and vendor management with the end-to-end view in mind

  • Demonstrated ability to effectively implement tools and techniques of project management, such as the development and management of integrated operational plans, critical path management, project risk management, decision analysis and meeting management in a fast-paced environment

  • Proven track record on delivering tasks with a commitment to continuous improvement for personal and team goals

  • Experience in generating executive-level communication and presentations in both written and visual (PowerPoint) mediums

  • Project Management Professional (PMP) certification or equivalent proficiency a plus

Key Competencies for Success

  • Significant attention to detail with strong planning and organizational skills

  • Able to influence and support the highly collaborative and inclusive environment necessary for the team to be effective

  • High-level of accountability; a driver with an exceptional ability to manage multiple tasks/projects in a fast-paced and matrixed environment with changing priorities and significant time pressures

  • Ability to take initiative, guide, and influence others toward goal accomplishment

  • Excellent skills in presentation development using PowerPoint and other media with very little oversight

  • Strong technical skills to set up templates and deliver solutions in different tools (Microsoft Excel and PowerPoint, Smartsheet, SharePoint, One Pager Pro, etc.)

  • Ability to manage and resolve complex operational issues, provide insight into complex multi-functional interdependencies, and to translate requirements into tangible deliverables

  • Critical thinking and problem solving; ability to contribute ideas to address business issues, ability to synthesize complex and diverse inputs to a problem, and recommend solutions/preferred options

  • This position can be based from any of the following Alexion locations; San Francisco, CA, Boston, MA, New Haven, CT, or Blue Bell, PA or be remote/virtual, based anywhere in the United states and may require up to 20% travel.


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Some opportunities happen only once in a lifetime - like a job where you have the extraordinary opportunity to change lives. At Alexion, such opportunities arise through our unwavering mission to serve patients and families affected by rare diseases. These patients are our guiding star, and we act with integrity, urgency, and discipline because we know their lives are at stake.

Alexion is a global biopharmaceutical company focused on serving patients and families affected by rare diseases and devastating conditions through the discovery, development and commercialization of life-changing medicines. As a leader in rare diseases for more than 25 years, Alexion has developed and commercializes two approved complement inhibitors to treat patients with paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS), as well as the first and only approved complement inhibitor to treat anti-acetylcholine receptor (AchR) antibody-positive generalized myasthenia gravis (gMG) and neuromyelitis optica spectrum disorder (NMOSD). Alexion also has two highly innovative enzyme replacement therapies for patients with life-threatening and ultra-rare metabolic disorders, hypophosphatasia (HPP) and lysosomal acid lipase deficiency (LAL-D) as well as the first and only approved Factor Xa inhibitor reversal agent. In addition, the company is developing several mid-to-late-stage therapies, including a copper-binding agent for Wilson disease, an anti-neonatal Fc receptor (FcRn) antibody for rare Immunoglobulin G (IgG)-mediated diseases and an oral Factor D inhibitor as well as several early-stage therapies, including one for light chain (AL) amyloidosis, a second oral Factor D inhibitor and a third complement inhibitor. Alexion focuses its research efforts on novel molecules and targets in the complement cascade and its development efforts on the core therapeutic areas of hematology, nephrology, neurology, metabolic disorders and cardiology. Headquartered in Boston, Massachusetts, Alexion has offices around the globe and serves patients in more than 50 countries. Further information about Alexion can be found at:

As a leading employer in our industry, Alexion is proud to offer a highly competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness and financial security of our employees and their families. Benefits include group medical, vision and dental coverage, group and supplemental life insurance, 401(k) with company match, tuition reimbursement, relocation assistance and much more.