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Alexion Pharmaceuticals Director, Global Program Management in Boston, Massachusetts

Some opportunities happen only once in a lifetime - like a job where you have the chance to change lives. At Alexion, people living with rare and devastating diseases are our Guiding Star. We are driven to continuously innovate and create meaningful value in all we do to help patients and families fully live their best lives. We value the uniqueness and diversity of our employees and recognize that nurturing the diverse perspectives and strengths of our people translates into innovative breakthroughs for patients.

This is what you will do:

The Director, Global Program Manager (GPM) is responsible for co-leading the strategic and operational planning and decision-making processes with an Alexion Global Program Team (GPT). Working in partnership with the Global Program Team Leader (GPTL), the GPM provides strategic vision and guidance to the team by developing integrated plans to successfully execute the strategy. The Director GPM will provide content expertise to the timing, costs, and resources required for development programs and be able to successfully deliver their program(s) milestones and goals. As the strategic partner and operational lead for development and lifecycle management programs, the Director GPM works to ensure that cross-functional teams operate effectively, fostering positive team dynamics and championing Alexion’s operating model.

You will be responsible for:

  • Leading cross functional GPTs, in partnership with the GPTL, to deliver key milestones and activities, and communicating program details, risks, and mitigations to Leadership Teams

  • Coordinating and driving the planning activities for the GPT, including milestone setting, budget forecasting, resource planning, scenario planning, and developing an integrated program plan based off of cross-functional inputs and assumptions

  • Providing strategic guidance to ‘pressure-test’ program team’s assumptions, drive scenario planning / trade off analysis, and cross-functional planning into the overall integrated program plan

  • Developing and maintaining program budget, resource planning and investment assumptions for buy-ups/buy-downs in partnership with finance to ensure transparency and accuracy of funding status

  • Facilitating team goal setting and tracking to ensure adherence to plan and strategy and in preparation for end of year team evaluation process

  • Managing all associated GPT sub-teams and tracking integrated deliverables, and preparing the GPT for governance interactions at program inflection points

  • Working independently to provide best in class operations and program management expertise to drive the GPT toward execution excellence, and bringing project management leadership and expertise in the assessment and integration of external assets into the Alexion pipeline

  • Representing the vision and mission of the department to the Alexion organization and provide mentorship to junior staff

    You will need to have:

    Given the complex, cross-functional, and cross-program nature of development programs; the GPM will need to execute in these core competencies:

  • Excellent written and verbal skills, strong influencing and interpersonal skills to operate and motivate a team in a matrix environment at all levels in the organization without authority

  • Must be well-organized and have strong attention to detail with an ability to deal with competing priorities; high level of problem-solving capability and business acumen, ability to balance competing priorities and quickly and objectively drive the team towards a path which maximizes value, while maintaining the end-to-end cross-functional view

  • Proven track record of planning and managing complex programs in different phases of development including cross-functional deliverables across Research, Operations, CMC, Commercial, and Market Access

  • Expert understanding of the end-to-end processes in drug development and product value assessment

  • Demonstrated ability to provide effective program management leadership in terms of setting program plans for the lifecycle of a program from discovery through launch

  • Expertise in budget and resource management and prioritization frameworks

  • Mastery of SharePoint, Microsoft Project, and knowledge of MS Project Server and technical proficiency in the use of program planning tools and systems (e.g., Microsoft Project, resource forecasting, decision analytics, budgets)

  • B.S. degree minimum, with higher level degree preferred, plus >10 years of industry experience, 8 of which should be in managing cross-functional teams

  • The duties of this role are generally conducted in an office environment. As is typical of an office-based role, employees must be able, with or without an accommodation to: use a computer; engage in communications via phone, video, and electronic messaging; problem solve; engage in complex and non-linear thought, analysis, and dialogue; collaborate with others; maintain general availability during standard business hours

    We would prefer for you to have:

  • MBA/M.S./M.A., or equivalent level of experience

  • 10+ years of experience within one or more functional role(s) in pharmaceutical R&D drug development, biotechnology, or related industry

  • Project Management Institute (PMI) qualifications or similar formal training preferred

  • High level of proficiency in MS Office software including: Word, Excel, Outlook, Visio, and PowerPoint



    Alexion is a global biopharmaceutical company focused on serving patients and families affected by rare diseases and devastating conditions through the discovery, development and commercialization of life-changing medicines. Headquartered in Boston, Massachusetts, Alexion has offices around the globe and serves patients in more than 50 countries. Further information about Alexion can be found at: .

    Alexion is proud to be an Equal Employment Opportunity and Affirmative Action employer. We are committed to fostering a culture of belonging where every single person can belong because of their uniqueness. The Company will not make decisions about employment, training, compensation, promotion, and other terms and conditions of employment based on race, color, religion, creed or lack thereof, sex, sexual orientation, age, ancestry, national origin, ethnicity, citizenship status, marital status, pregnancy, (including childbirth, breastfeeding, or related medical conditions), parental status (including adoption or surrogacy), military status, protected veteran status, disability, medical condition, gender identity or expression, genetic information, mental illness or other characteristics protected by law. Alexion has taken critical steps to protect colleagues, loved ones, and patients from COVID-19 and its variants. All US-based employees must comply with Alexion's COVID-19 vaccination mandate. Alexion provides exceptions based on applicable state law as well as reasonable accommodations to meet the needs of candidates and employees. To begin an interactive dialogue with Alexion regarding a legally required exemption or accommodation, please contact Alexion participates in E-Verify.

    As a leading employer in our industry, Alexion offers a highly competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness and financial security of our employees and their families. Benefits include group medical, vision and dental coverage, group and supplemental life insurance, 401(k) with company match, tuition reimbursement, and much more.

    AstraZeneca completed its acquisition of Alexion, marking the creation of Alexion, AstraZeneca Rare Disease. If you're interested in career opportunities with AstraZeneca, click here ( .