Merck Senior Scientist, Informatics and Analytics in Boston, Massachusetts

Merck & Co., Inc. Kenilworth, N.J., U.S.A. known as Merck in the United States and Canada, is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. The difference between potential and achievement lies in the spark that fuels innovation and inventiveness; this is the space where Merck has codified its legacy for over a century. Merck’s success is backed by ethical integrity, forward momentum, and an inspiring mission to achieve new milestones in global healthcare.

We are seeking a highly motivated Computational Biology scientist to join our Global Research IT team at Merck. As a scientist in Research IT organization, the successful candidate will partner with biologists in Merck Research Labs and apply advanced computational methods and data analytics for target identification, target validation and biomarker discovery. The role will focus on developing quantitative methods, machine learning applications and visual analytics and analyzing multi-dimensional data sets to support Merck’s drug discovery biology and translation medicine research.

Job responsibilities:

  • Develop computational methods and perform analysis of datasets from next-generation sequencing applications and high-content screening

  • Integrate internal and public available databases in omics, pathways and genetics and apply machine learning to identify novel drug targets and biomarkers

  • Proactively engage with biology, genetics, pharmacology and biomarker teams in Merck Research Labs to identify collaborative projects and serve as a site-based Computational Biology liaison

  • Contribute novel bioinformatics algorithms and data computing pipelines to the global Computational Biology network and support cross-site translational informatics projects

Education Minimum Requirement:

  • A Master degree or a Ph.D. degree with a focus on computational biology, bioinformatics, or computer science or related fields.

Required Experience and Skills:

  • A minimum of 5 years industrial experience for Master degree and up to 1 year for Ph.D. degree in computational biology, bioinformatics, or machine learning

  • A demonstrated track record of developing computational methods and pipeline for biology discovery or genomics technology

  • Extensively experience in using the workflow framework to develop next-generation sequencing data analysis pipelines such as whole genome sequencing, or exome sequencing, or transcriptome sequencing

  • Proficiency in programming languages (Python, Perl, C ), and mathematical and statistical package, such as R and MatLab, in a Unix/Linux environment

  • Experience with high-performance Linux cluster and cloud computing

  • Excellent interpersonal and team skills

  • Demonstrated ability to collaborate with cross-functional project teams

  • A proven track record of scientific publications

  • Excellent oral and written communication skills in English

Preferred Experience and Skills:

  • Knowledge of disease biology including Cardiovascular and Metabolic Disease and Immuno-oncology;

  • Knowledge of high content screening and imaging analytics

  • Hands-on experience by applying machine learnings

Your role at Merck is integral to helping the world meet new breakthroughs that affect generations to come, and we’re counting on your skills and inventiveness to help make meaningful contributions to global medical advancement. At Merck, we’re inventing for life.

If you need assistance and/or a reasonable accommodation due to a disability during the application or the recruiting process, please send a request to staffingaadar@merck.com .

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Merck is an equal opportunity employer, Minority/Female/Disability/Veteran – proudly embracing diversity in all of its manifestations.

Job Informatics & Analytics

Merck is an equal opportunity employer, Minority/Female/Disability/Veteran – proudly embracing diversity in all of its manifestations.

Other Locations: NA-US-MA-Boston

Title: Senior Scientist, Informatics and Analytics

Primary Location: NA-US-CA-South San Francisco

Requisition ID: INF004815