AstraZeneca Pharmaceuticals LP High Performance Computing Engineer (HPC) - SEUIT in Waltham, Massachusetts

High Performance Computing Engineer – Waltham, MA

At AstraZeneca, science is at the core of everything we do. But more than that, science is who we are. Our research sites are collaborative, innovative and dynamic environments that allow our scientists to keep pushing the boundaries. We work alongside scientists at leading institutions to better understand disease, identify potential new drugs and accelerate drug development. We’re also pioneers in creating a more open research environment.

One of the pillars enabling our science is our scientific computing capability to solve ever-changing and complex data and computing problems. Leading edge advances in science are driving storage & computational needs. Partnerships and external collaborations are demanding more effective ways to share data & analytical tools. To bolster our innovation-driven science we are now investing in the next generation scientific computing environment for science research across the globe.

Scientific computing is a strategic asset for AstraZeneca. We are looking for a hands-on DevOps operational leader who can drive the release, deployment, operations and monitoring of our scientific computing platforms available to all science units across the globe.

You will be part of our global operations team running the platform. Experience in operating a high-performance computing (HPC) environment is a must. We seek a “do-er” who manages and develops relationships with the science units to explore innovative ways to address the computational and informatics needs of the science community globally.

Company Description

AstraZeneca is a global, innovation-driven biopharmaceutical business that focuses on the discovery, development and commercialization of prescription medicines for some of the world's most serious diseases. AstraZeneca is one of only a handful of pure-play biopharmaceutical companies to span the entire value chain of a medicine from discovery, early- and late-stage development to manufacturing and distribution, and the global commercialisation of primary care, specialty care-led and specialty care medicines that transform lives.

Our primary focus is on three key areas of healthcare: Cardiovascular and Metabolic disease (CVMD); Oncology; and Respiratory, Inflammation and Autoimmunity (RIA). We are also active in the Infection, Neuroscience and Gastrointestinal (ING) disease areas.

Overview of Science IT

The purpose of the Science IT division within AstraZeneca is to partner with the Drug R&D teams to provide world-class Informatics and in Scientific Information & Technology solutions to accelerate the drug pipeline. Delivering the Science IT portfolio of projects and services needs a team with a hybrid skill set of technical ability and knowledge of the R&D processes.


  • Responding quickly and effectively to a range of requests on the HPC platform, ultimately ensuring availability and stability of the platform to our Science Units

  • Diagnosing and solving issues and problems

  • Manage and develop relationships with our science teams to understand computational challenges and bring forward solutions utilizing the HPC platform

  • Contribute to a clear roadmap for operational excellence of our platform

  • Providing technical input across projects using

Experience required

  • Strong evidence of hands-on experience designing and configuring large-scale HPC environments,

  • Experience providing scientific software for users: configuring, installing, tuning and maintaining such software

  • Experience of cloud computing infrastructure (e.g. AWS, Google, Azure) is a plus.

  • Configuration management experience (e.g. chef, salt, puppet, ansible, cfengine)

  • Experience in managing a virtualized private cloud environment (e.g. OpenStack)

  • Experience with container technology e.g LXD, Singularity to Docker is a plus

  • Demonstrated development experience with a variety of programming languages, tools and technologies (Java/C++, Python/Ruby/Perl, SQL, AWS) is a plus

  • Experience of developing and managing relationships with 3rd party suppliers

  • Bachelor’s degree in Computational, Physical or Biological Science, Engineering or equivalent area (Masters or PhD preferred)

  • Experience in high-performance scientific computing

  • Experience within a research-based scientific computing environment a plus, preferably Life Sciences (Pharma, BioTech)

Apply now to learn more about this exciting opportunity with a world renowned pharmaceutical brand!

To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience – it is the only way that our Recruiter and Hiring Manager can know that you feel well qualified for this opportunity. If you know someone who would be a great fit, please share this posting with them.

AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law.