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Sanofi Group Senior Associate Engineer - Vaccine in Waltham, Massachusetts

In the race for the future of health – The Sanofi mRNA Center of Excellence (CoE)

At Sanofi, we chase the miracles of science, and we know mRNA has a role to play in the future of health. And while the pandemic has shaken up our industry, creating new opportunities and risks, we believe the acceleration of innovation with mRNA technology means vaccines and treatments for more people faster than before.

That’s why we’re looking for bold, optimistic world-changers to join our mRNA Center of Excellence. We’re investing €400m a year into the new Center, hiring a team of 450 dedicated employees, and focusing on implementing an integrated end-to-end mRNA vaccine capabilities and research with R&D, digital and CMC teams.

Watch our Jobinar’s replay ( ) to discover more about the ongoing work at our Center of Excellence.

Bring your ambition and optimism and join us on our journey to discover and deliver transformative medicine to patients through the advancement of our cutting-edge mRNA technology!


The Associate Engineer reports to the Director of Process Development and focuses on optimization and scale-up of Lipid Nanoparticle (LNP) formulations in support of all therapeutic and vaccine related programs at Sanofi.


  • Lead and support the optimization and scale-up of Bulk Drug Product (BDP) formulation and Final Drug Product (FDP) processes encompassing a wide range of different DS and multi-component LNPs

  • Perform routine and complex analytical methods with minimal supervision

  • Keep detailed records using an electronic laboratory notebook

  • Present experimental results to group and CMC teams as needed

  • Critical thinking and analysis of data will be central to all aspects of this position

  • Design, procure, and maintain equipment in the Process Development lab and pilot plant

  • Produce materials that is representative of cGMP material and suitable for nonclinical studies including GLP toxicology studies

  • Assist with preparation of technical reports and presentations to clearly communicate scientific findings as needed


  • BS/MS degree, preferably in Chemical Engineering/Biochemistry or in a similar field is required

  • 2 – 4 years' experience working in a process development or tech transfer environment is required


  • Capable of working in a collaborative team environment both within group and on interdisciplinary teams

  • Desire to work in a fast-paced environment

  • Excellent organizational and communication skills

  • Strong analytical and problem-solving skills

  • Ability to present findings to a diverse scientific group in a clear and concise manner is necessary


  • Candidate with process development knowledge is highly desirable

  • Experience with LNP formulations of mRNA/siRNA would be beneficial

  • Previous work with mRNA (handling/isolation/quantification/characterization) is desired

  • Knowledge of mRNA and LNP characterization methods preferred


Work is performed in an office and laboratory environment with routine lab physical demands and normal exposure to everyday risks and discomfort requiring common safety precautions.

This job description is intended to describe the general nature and level of the work being performed by employees in the position. It is not intended to be a complete list of all responsibilities, duties, and skills for the position. The Company reserves the right at all times, in its sole discretion, to add or subtract duties and responsibilities, as it deems necessary.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

As a healthcare company and a vaccine manufacturer, Sanofi has an important responsibility to protect individual and public health. All US based roles require individuals to be fully vaccinated against COVID-19 as part of your job responsibilities.

According to the CDC, an individual is considered to be “fully vaccinated” fourteen (14) days after receiving (a) the second dose of the Moderna or Pfizer vaccine, or (b) the single dose of the J&J vaccine. Fully vaccinated, for new Sanofi employees, is to be fully vaccinated 14 DAYS PRIOR TO START DATE.



At Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.